Product Description

VILIP-1 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67049-50, MB67049-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Visinin-like Protein 1, also called VILIP-1 and VSNL1, is a calcium-sensing protein in the central nervous system. Visinin-like Protein 1 exhibits a widespread distribution with high expression in the CNS, and lower expression levels in some peripheral tissues . Visinin-like Protein 1 responds to increased intracellμlar calcium concentration by translocating from the cytoplasm to membranes through calcium-dependent myristoylation at its N-terminus that allows interaction with membranes . This change in localization has been proposed to facilitate the activation of compartment-specific signal transduction for the selective activation of downstream signaling cascades . In Alzheimer’s disease, Visinin-like Protein 1 expression is decreased in the brain, including a reduced number of Visinin-like Protein 1 immunoreactive neurons , however, the presence of the protein is increased in the CSF , suggesting that it is released from neurons during insμlts.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: VISL1, Visinin-like protein 1, VILIP, VLP-1, Hippocalcin-like protein 3, HLP3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human VILIP-1. The exact sequence is proprietary.

Dilution: WB (1/1000 - 1/2000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of VILIP-1 protein.

Molecular Weight: ~ 18 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P62760

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only