Vimentin (phospho Ser83) rabbit pAb - ES7506

Vimentin (phospho Ser83) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7506-50, ES7506-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],

Alternate Name: VIM; Vimentin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Vimentin around the phosphorylation site of Ser83. AA range:56-105

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 54kD

Human Gene ID: 7431

Human SWISS Prot NO: P08670

Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.

Research Use Only