Vimentin (Phospho-Tyr38) rabbit pAb - ES8459

Vimentin (Phospho-Tyr38) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8459-50, ES8459-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],

Alternate Name: VIM

Source: Rabbit

Applications: WB; ELISA

Dilution: WB: 1:500-10000 ELISA: 1:10000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 51kD

Human Gene ID: 7431

Human SWISS Prot NO: P08670

Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.

Research Use Only