Vitronectin rabbit pAb - ES8386

Vitronectin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8386-50, ES8386-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008],

Alternate Name: VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human VTN. AA range:50-100

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 7448

Human SWISS Prot NO: P04004

Subcellular Location: Secreted, extracellular space.; Parasitophorous vacuole. (Microbial infection) In P.falciparum-infected red blood cells, VTN internalization is detected at the early trophozoite stage (PubMed:29567995). Colocalizes with SERA5 at the schizont stage and with SERA5 P47 at the merozoite surface (PubMed:29567995).

Research Use Only