Product Description

VMA21 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53204-60, E-AB-53204-120, E-AB-53204-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: VMA21

Target Synonym: VMA21; Vacuolar ATPase Assembly Factor; Myopathy With Excessive Autophagy Protein; MEAX; XMEA; Vacuolar ATPase Assembly Integral Membrane Protein VMA21; VMA21 Vacuolar H+-ATPase Homolog (S. Cerevisiae); Myopathy With Excessive Autophagy; VMA21 Vacuolar H+-ATPase Homolo.

Research Areas: Cell Biology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, IF, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q3ZAQ7

Background: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.

Concentration: 2.6 mg/mL

Immunogen: Synthetic peptide of human VMA21

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:150-1:500, IF 1: 50-1:200, ELISA 1:5000-1:240000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only