VNN1 Polyclonal Antibody - E-AB-53205

VNN1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53205-60, E-AB-53205-120, E-AB-53205-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: VNN1

Target Synonym: HDLCQ8; High density lipoprotein cholesterol level quantitative trait locus 8; included; Pantetheinase; Pantetheine hydrolase; Tiff66; V-1; Vanin 1; Vanin-1; Vannin 1; Vascular non inflammatory molecule 1; Vascular non-inflammatory molecule 1; VNN 1; VNN1; VNN1

Research Areas: Cell Biology, Cardiovascular, Metabolism, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IF, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O95497

Background: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

Concentration: 1.7 mg/mL

Immunogen: Synthetic peptide of human VNN1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IF 1: 100-1:500, ELISA 1:5000-1:240000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only