Product Description

VPS11 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS72335-50, BS72335-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9H270

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB IF

All Applications: WB 1:500 - 1:2000
IF 1:50 - 1:200

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: VPS11 polyclonal antibody detects endogenous levels of VPS11 protein.

Bioworld Molecular Weight: ~ 108 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of mouse pancreas, using VPS11 antibody.

Alternative Name: END1; HLD12; hVPS11; PEP5; RNF108

Immunogen: Recombinant protein of human VPS11

Conjugate: Unconjugated

Modification: Unmodified