WAVE1 Polyclonal Antibody - RA21301

WAVE1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21301-50, RA21301-100

Citations, Manuals and MSDS Available upon request.

Background: WAS protein family member 1 (WASF1) Homo sapiens The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) -family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: WASF1; KIAA0269; SCAR1; WAVE1; Wiskott-Aldrich syndrome protein family member 1; WASP family protein member 1; Protein WAVE-1; Verprolin homology domain-containing protein 1

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 8936

Protein MW (KDa): 70

SWISS: Q92558

Source: Rabbit

Research Use Only