WBS22 rabbit pAb - ES12327

WBS22 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12327-50, ES12327-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2011],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human WBS22 AA range: 144-194

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 114049

Human SWISS Prot NO: O43709

Subcellular Location: Nucleus. Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Cytoplasm. Localized diffusely throughout the nucleus and the cytoplasm (PubMed:24488492). Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes (PubMed:25851604). Localization is not affected by glucocorticoid treatment (PubMed:24488492).

Research Use Only