WDR62 rabbit pAb - ES12315

WDR62 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12315-50, ES12315-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human WDR62 AA range: 984-1034

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 284403

Human SWISS Prot NO: O43379

Subcellular Location: Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis. Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles.

Research Use Only