Product Description

WDSUB1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53557-60, E-AB-53557-120, E-AB-53557-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: WDSUB1

Target Synonym: 1700048E19Rik; 2610014F08Rik; FLJ36175; MGC108920; UBOX6 ; WD repeat; SAM and U box domain containing protein 1; WD repeat; SAM and U-box domain containing 1; WD repeat; sterile alpha motif and U box domain containing 1 ; WDSAM1 ; WDSUB1

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8N9V3

Background: WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1, 400 genes and comprises nearly 8% of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human WDSUB1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Calculated MW: 53 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only