WIPI2 Rabbit rabbit pAb - ES20596

WIPI2 Rabbit rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20596-50, ES20596-100

Citations, Manuals and MSDS Available upon request.

Background: WD repeat domain, phosphoinositide interacting 2 (WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008],

Alternate Name: WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2; WIPI49-like protein 2)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Recombinant Protein of WIPI2

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 49kD

Human Gene ID: 26100

Human SWISS Prot NO: Q9Y4P8

Subcellular Location: Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side. Localizes to omegasomes membranes which are endoplasmic reticulum connected structures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P.

Research Use Only