WN10A Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36190-50, RA36190-100 Citations, Manuals and MSDS Available upon request. Background: Wnt family member 10A (WNT10A) Homo sapiens The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 80326 Protein MW (KDa): 45 SWISS: Q9GZT5 Source: Rabbit Research Use Only