WNK4 Polyclonal Antibody - BT-AP15547

WNK4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15547-20, BT-AP15547-50, BT-AP15547-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

Research Areas: Signal transduction

Target Protein: WNK4

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine/threonine-protein kinase WNK4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96J92; Mouse: Q80UE6; Rat: Q7TPK6

Synonyms: Serine/threonine-protein kinase WNK4;EC 2.7.11.1;Protein kinase lysine-deficient 4;Protein kinase with no lysine 4

GeneID: Human: 65266

Research Use Only