Wnt1 Polyclonal Antibody-BZ16122

Wnt1 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16122-50, BZ16122-100

Swiss-Prot: P04628

Host: Rabbit

Wnt1 Polyclonal Antibody-BZ16122

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IHC-F, IHC-P, ICC/IF, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: WNT1: wingless-type MMt V integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 41 kDa; Observed MW: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Wnt1 in variousLysates using Wnt1 antibody., Western blot analysis of Wnt1 in HT-29Lysates using Wnt1 antibody.

Alternative Name: WNT1; INT1; Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog

Immunogen: The antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350

Modification: Unmodified

Conjugate: Unconjugated