Product Description

WNT3A Monoclonal Antibody

Catalogue Numbers: MB66610-50, MB66610-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P56704

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity).Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).A palmitoylation site was proposed at Cys-77, but it was later shown that this cysteine is engaged in a disulfide bond.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of WNT3A protein.

Extra Notes: Western blot analysis of WNT3A expression in MCF7 (A), ZR751 (B), MDAMB468 (C), T47D (D) whole cell lysates.

Bioworld Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Protein Wnt-3a

Immunogen: Purified recombinant Wnt3a protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified