Wnt5a Monoclonal Antibody-MB11783

Wnt5a Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11783-50, MB11783-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P41221

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 42 kDa; Observed MW: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Wnt5a in Hela lysates using Wnt5a antibody., Immunocytochemistry analysis of Wnt5a in hela using Wnt5a antibody, and DAPI

Alternative Name: WNT5A; Protein Wnt-5a

Immunogen: A synthetic peptide of human Wnt5a

Conjugate: Unconjugated

Modification: Unmodified