Wnt5a Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16808-50, BZ16808-100
Swiss-Prot: P41221
Host: Rabbit
Reactivity: Human
Applications: WB, ICC/IF, FC
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 42 kDa; Observed MW: 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Wnt5a in HeLa lysates using Wnt5a antibody.
Alternative Name: WNT5A; Protein Wnt-5a
Immunogen: A synthesized peptide derived from human Wnt5a
Conjugate: Unconjugated
Modification: Unmodified