WTAP rabbit pAb - ES3707

WTAP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3707-50, ES3707-100

Citations, Manuals and MSDS Available upon request.

Background: The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012],

Alternate Name: WTAP; KIAA0105; Pre-mRNA-splicing regulator WTAP; Female-lethal (2)D homolog; hFL (2)D; WT1-associated protein; Wilms tumor 1-associating protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human WTAP. AA range:321-370

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 9589

Human SWISS Prot NO: Q15007

Subcellular Location: Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm. Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus.

Research Use Only