Product Description

XBP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12306-50, MB12306-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P17861

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 29 kDa; Observed MW: 29 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of XBP1 in Raw264.7 lysates using XBP1 antibody., Western blot analysis of XBP1 in HL-60, U2OS lysates using XBP1 antibody.

Alternative Name: XBP1; TREB5; XBP2; X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5

Immunogen: Recombinant protein of human XBP1

Conjugate: Unconjugated

Modification: Unmodified