XCL1/2 Polyclonal Antibody
Catalogue Numbers: BS60985-50, BS60985-100
Sizes: 50µl, 100µl
Alternative Name: Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL1; LTN; SCYC1; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2; XCL2; SCYC2
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P47992/Q9UBD3
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells. Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines. In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary. Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes. The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family. The gene which encodes lymphotactin maps to human chromosome 1q23.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: XCL1/2 polyclonal antibody detects endogenous levels of XCL1/2 protein.
Bioworld Molecular Weight: ~ 13 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of XCL1/2 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human XCL1.
Conjugate: Unconjugated
Modification: Unmodified