Product Description

XDH Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15568-20, BT-AP15568-50, BT-AP15568-100

Citations, Manuals and MSDS Available upon request.

Background: Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

Research Areas: Signal transduction; Metabolism

Target Protein: XDH

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P47989; Mouse: Q00519; Rat: P22985

Synonyms: Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase;XD;EC 1.17.1.4; Xanthine oxidase;XO;EC 1.17.3.2;Xanthine oxidoreductase;XOR]

GeneID: Human: 7498

Research Use Only