Product Description

XIAP Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11786-50, MB11786-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q60989

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of XIAP in K562, rat Brain, 3T3Lysates using XIAP antibody.

Bioworld Molecular Weight: Calculated MW: 56 kDa; Observed MW: 53 kDa

Specificity: IgG

Alternative Name: API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3

Immunogen: Recombinant protein of mouse XIAP

Conjugate: Unconjugated

Modification: Unmodified