Product Description

XPD Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11788-50, MB11788-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P18074

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of XPD in Jurkat, Hela lysates using XPD antibody., Immunocytochemistry analysis of XPD in Hela using XPD antibody, and DAPI

Alternative Name: BTF2 p80; COFS2; CXPD; EM9; ERCC2; MAG; TFIIH p80; TTD; XPD; XPDC

Immunogen: A synthetic peptide of human XPD

Conjugate: Unconjugated

Modification: Unmodified