XRCC1 Monoclonal Antibody-MB66594

XRCC1 Monoclonal Antibody

Catalogue Numbers: MB66594-50, MB66594-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P18887

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: The X-ray repair cross complementing protein 1 (XRCC1) is a DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents. XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins. At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK, DNA ligase III, poly (ADP-ribose) polymerase, and PCNA. Mutations and polymorphisms in the XRCC1 gene serve as diagnostic markers and are associated with elevated risk of various forms of cancers.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of XRCC1 protein.

Extra Notes: Western blot analysis of XRCC1 expression in Raji (A), K562 (B), Hela (C), Jurkat (D), THP1 (E) whole cell lysates.

Bioworld Molecular Weight: ~ 82 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: DNA repair protein XRCC1; X-ray repair cross-complementing protein 1

Immunogen: Purified recombinant human XRCC1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified