Product Description

XRCC4 (7C10) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB3188-50, MB3188-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, IHC-F, IHC-P, ICC/IF, IP

Alternate Names: X ray repair cross complementing protein 4, DNA repair protein XRCC4, DNA double strand break repair

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic Peptide of XRCC4

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Purification: Affinity Purified

Specificity: IgG1

Molecular Weight: Calcμlated MW: 38 kDa, Observed MW: 38-45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13426

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only