XRCC4 Monoclonal Antibody (5C10) - BT-MCA0081

XRCC4 Monoclonal Antibody (5C10)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0081-20, BT-MCA0081-50, BT-MCA0081-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Research Areas: Epigenetics and nuclear signaling

Target Protein: XRCC4

Applications: WB, IHC-p, IF, ICC, IP

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: DNA repair protein XRCC4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 38287

UniProt Accession: Human: Q13426; Mouse: Q924T3

Synonyms: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

GeneID: Human: 7518; Mouse: 108138

Research Use Only