XRCC4 rabbit pAb - ES3716

XRCC4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3716-50, ES3716-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],

Alternate Name: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 7518

Human SWISS Prot NO: Q13426

Subcellular Location: Nucleus. Chromosome. Localizes to site of double-strand breaks.; [Protein XRCC4, C-terminus]: Cytoplasm. Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3).

Research Use Only