XRCC6 Monoclonal Antibody - BT-MCA2290

XRCC6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2290-50, BT-MCA2290-100

Citations, Manuals and MSDS Available upon request.

Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: XRCC6

Applications: WB, IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2F7F5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: XRCC6

Immunogen: Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 69.8kDa

UniProt Accession: P12956

Synonyms: ML8, KU70, TLAA, CTC75, CTCBF, G22P1

GeneID: 2547

Research Use Only