XRN1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36244-50, RA36244-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: 5'-3' exoribonuclease 1 (XRN1) Homo sapiens This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 187 Protein Molecular Weight (kDa): 187 Storage: -20°C/1 year Human Gene ID: 54464 Human SwissProt Number: Q8IZH2 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only