XRN1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36244-50, RA36244-100 Citations, Manuals and MSDS Available upon request. Background: 5'-3' exoribonuclease 1 (XRN1) Homo sapiens This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 54464 Protein MW (KDa): 187 SWISS: Q8IZH2 Source: Rabbit Research Use Only