YAP1 Monoclonal Antibody-MB11791

YAP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11791-50, MB11791-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P46937

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of YAP1 in Hela lysates using YAP1 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using YAP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Immunogen: A synthetic peptide of human YAP1

Conjugate: Unconjugated

Modification: Unmodified