Product Description

YEATS2 Polyclonal Antibody

Catalogue Numbers: BS5668-50, BS5668-100

Sizes: 50µl, 100µl

Alternative Name: YEATS domain-containing protein 2; YETS2; KIAA1197

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9ULM3

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: The YEATS domain-containing protein 2 (YEATS2) is a nuclear protein that is phosphorylated upon DNA damage by ATM or ATR and contains 1 YEATS domain. The gene encoding YEATS2 resides on chromosome 3, which contains about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: YEATS2 polyclonal antibody detects endogenous levels of YEATS2 protein.

Bioworld Molecular Weight: ~ 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of YEATS2 pAb at 1:500 dilution
Lane 1: A2780 whole cell lysate(40ug)
Lane 2: MCF-7 whole cell lysate(40ug)
Lane 3: SK-OVCAR3 whole cell lysate(40ug)
Lane 4: HEK293T whole cell lysate(40ug)
Lane 5: A549 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 393-438 of Human YEATS2.

Conjugate: Unconjugated

Modification: Unmodified