Product Description

YY1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16561-50, BZ16561-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: P25490

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 45 kDa; Observed MW: 68 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of YY1 in HeLa lysates; Daudi lysates using YY1 antibody., Immunohistochemistry analysis of paraffin-embedded Human bladder using YY1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of YY1 in Hela using YY1 antibody.

Alternative Name: YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1

Immunogen: A synthesized peptide derived from human YY1

Conjugate: Unconjugated

Modification: Unmodified