Z280B Polyclonal Antibody - BT-AP15594

Z280B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15594-20, BT-AP15594-50, BT-AP15594-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding.

Research Areas: Epigenetics and nuclear signaling

Target Protein: ZNF280B

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Zinc finger protein 280B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q86YH2

Synonyms: Zinc finger protein 280B;5'OY11.1;Suppressor of hairy wing homolog 2;Zinc finger protein 279;Zinc finger protein 632

GeneID: Human: 140883

Research Use Only