Product Description

ZAC1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09642-20, BT-AP09642-50, BT-AP09642-100

Citations, Manuals and MSDS Available upon request.

Background: PLAGL1 encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.

Research Areas: Neuroscience

Target Protein: PLAGL1

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ZAC1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 50819

UniProt Accession: Human: Q9UM63

Synonyms: PLAGL1; LOT1; ZAC; Zinc finger protein PLAGL1; Lost on transformation 1; LOT-1; Pleiomorphic adenoma-like protein 1; Tumor supressor ZAC

GeneID: Human: 5325

Research Use Only