Product Description

ZAP-70 Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA12199-50, RA12199-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: zeta chain of T cell receptor associated protein kinase 70 (ZAP70) Homo sapiens This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Mouse

Applications: WB, IP

Alternate Names: 70 kDa zeta associated protein, 70 kDa zeta-associated protein, EC 2.7.10.2, FLJ17670, FLJ17679, Selective T cell defect, SRK, STD, Syk related tyrosine kinase, Syk-related tyrosine kinase, Truncated ZAP kinase, Tyrosine protein kinase ZAP70, Tyrosine-protein kinase ZAP-70, TZK, ZAP 70, ZAP-70, ZAP70, ZAP70_HUMAN, Zeta chain associated protein kinase 70kD, Zeta chain associated protein kinase 70kDa, Zeta chain associated protein kinase 70kDa isoform 1, Zeta chain associated protein kinase 70kDa isoform 2, Zeta chain TCR associated protein kinase 70kD, Zeta chain TCR associated protein kinase 70kDa.

Clonality: Monoclonal

Dilution: wb dilution 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 7535

Protein Molecular Weight（KDa): 70

Molecular Weight: 70

Research Use Only