Product Description

ZBTB10 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19551-60, E-AB-19551-120, E-AB-19551-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZBTB10

Target Synonym: FLJ12752; OTTHUMP00000207119; RINZF; RINZFC; ZBT10; ZBTB10; Zinc finger and BTB domain containing protein 10; Zinc finger and BTB domain-containing protein 10; Zinc finger protein RIN ZF

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96DT7

Background: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

Concentration: 1.7 mg/mL

Immunogen: Synthetic peptide of human ZBTB10

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Calculated MW: 95 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only