ZBTB16 Monoclonal Antibody - BT-MCA3212

ZBTB16 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3212-50, BT-MCA3212-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Research Areas: Stem cells, Cancer, Epigenetics and nuclear signaling, Developmental biology

Target Protein: ZBTB16

Applications: WB, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5B3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ZBTB16

Immunogen: Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 74kDa

UniProt Accession: Q05516

Synonyms: PLZF, ZNF145, ZBTB16

GeneID: 7704

Research Use Only