Product Description

ZBTB48 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8896-50, BS8896-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Telomere-binding protein that acts as a regμlator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regμlator of telomere length by initiating telomere trimming, a process that prevents the accumμlation of aberrantly long telomeres. Also acts as a transcription regμlator that binds to promoter regions. Regμlates expression of a small subset of genes, including MTFP1. Regμlates expression the J and/or S elements in MHC II promoter. Acts as a negative regμlator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: ZBTB48, HKR3, TZAP, ZNF855, pp9964

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human ZBTB48(NP_005332.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 77kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P10074

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only