ZBTB48 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91463-50, BS91463-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P10074(Human) Q1H9T6(Mouse)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200
Background: Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: ZBTB48 polyclonal antibody detects endogenous levels of ZBTB48 protein.
Bioworld Molecular Weight: 77 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ZBTB48 on mouse spleen tissue lysate using anti-ZBTB48 antibody at 1/1,000 dilution., ICC staining ZBTB48 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: TZAP, hKR3, ZBTB48, HKR3, TZAP, ZNF855, 0610011D15Rik, AI327031, GLI Kruppel family member HKR3, HKR3, Krueppel related zinc finger protein 3, Krueppel-related zinc finger protein 3, OTTMUSP00000031803, pp9964, Protein HKR3, RP23-445E20.3, ZBT48, ZBTB 48, Zbtb48, Zinc finger and BTB domain containing 48, Zinc finger and BTB domain containing protein 48, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855, ZNF855,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodified