Product Description

ZC3H11A Polyclonal Antibody

Catalogue Numbers: BS5978-50, BS5978-100

Sizes: 50µl, 100µl

Alternative Name: Zinc finger CCCH domain-containing protein 11A; KIAA0663; ZC3HDC11A

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75152

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: ZC3H11A (zinc finger CCCH domain-containing protein 11A), also known as KIAA0663 or ZC3HDC11A, is an 810 amino acid protein that contains 3 C3 H1-type zinc fingers. ZC3H11A is expressed in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, fetal brain and fetal liver. The gene encoding ZC3H11A maps to human chromosome 1q32.1 and mouse chromosome 1 E4. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene on chromosome 1 which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZC3H11A polyclonal antibody detects endogenous levels of ZC3H11A protein.

Bioworld Molecular Weight: ~ 89 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ZC3H11A polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 339-384 of Human ZC3H11A.

Conjugate: Unconjugated

Modification: Unmodified