Product Description

ZCCHC17 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61229-50, BS61229-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3, 000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson’s disease, Gaucher disease and Usher syndrome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Nucleolar protein of 40 kDa, pNO40, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, PS1D protein, Zinc finger CCHC domain-containing protein 17, ZCCHC17, PS1D

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human ZCCHC17.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ZCCHC17 polyclonal antibody detects endogenous levels of ZCCHC17 protein.

Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NP64

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only