Product Description

ZDHHC15 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62420-50, BS62420-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Palmitoyltransferase ZDHHC15, palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Palmitoylates IGF2R and SORT1, promoting their partitioning to an endosomal membrane subdomain where they can interact with the retromer cargo-selective complex. Thereby, regμlates retrograde transport from endosomes to the Golgi apparatus of these lysosomal sorting receptors and plays a role in trafficking of lysosomal proteins. In the nervous system, catalyzes the palmitoylation of DLG4/PSD95 and regμlates its synaptic clustering and function in synaptogenesis. Coμld be involved in the differentiation of dopaminergic neurons and the development of the diencephalon. Coμld also catalyze the palmitoylation of GAP43. Coμld also palmitoylate DNAJC5 and regμlate its localization to the Golgi membrane. Coμld also palmitoylate FYN as shown in vitro.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Palmitoyltransferase ZDHHC15, Acyltransferase ZDHHC15, Zinc finger DHHC domain-containing protein 15, DHHC-15, ZDHHC15, UNQ1969, PRO4501

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human ZDHHC15.

Dilution: WB:1:500~1:1000

Purification: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Specificity: ZDHHC15 polyclonal antibody detects endogenous levels of ZDHHC15 protein.

Molecular Weight: ~ 39 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96MV8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only