ZDHHC18 Polyclonal Antibody
Catalogue Numbers: BS60611-50, BS60611-100
Sizes: 50µl, 100µl
Alternative Name: Palmitoyltransferase ZDHHC18; Zinc finger DHHC domain-containing protein 18; DHHC-18; ZDHHC18
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9NUE0
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ZDHHC18 polyclonal antibody detects endogenous levels of ZDHHC18 protein.
Bioworld Molecular Weight: ~ 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ZDHHC18 polyclonal antibody at 1:500 dilution
Lane 1: A549 whole cell lysate
Lane 2: MCF-7 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human ZDHHC18
Conjugate: Unconjugated
Modification: Unmodified