ZFP42 Polyclonal Antibody - E-AB-16185

ZFP42 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16185-60, E-AB-16185-120, E-AB-16185-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZFP42

Target Synonym: hREX-1; Reduced Expression 1 Protein; Reduced expression protein 1; Rex-1; REX1; REX1 transcription factor; Zfp-42; Zfp42; ZFP42 zinc finger protein; ZFP42; Zinc finger protein 42 homolog; Zinc finger protein 754; ZNF754

Research Areas: Cancer, Developmental Biology, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96MM3

Background: Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human ZFP42

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Calculated MW: 35kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only