ZFYV1 rabbit pAb - ES12205

ZFYV1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12205-50, ES12205-100

Citations, Manuals and MSDS Available upon request.

Background: The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human ZFYV1 AA range: 318-368

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 53349

Human SWISS Prot NO: Q9HBF4

Subcellular Location: Golgi apparatus Golgi stack. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Preautophagosomal structure. Mitochondrion. Resides predominantly in the cisternal stacks of the Golgi (PubMed:11256955). Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (PubMed:22178386). During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (PubMed:31293035, PubMed:25876663). Localizes to lipid droplets in the presence of oleic acid (PubMed:31293035, PubMed:30970241).

Research Use Only