Product Description

ZIC2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS72739-50, BS72739-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O95409

Host: Rabbit

Reactivity: Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZIC2 polyclonal antibody detects endogenous levels of ZIC2 protein.

Bioworld Molecular Weight: 50kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using ZIC2 antibody.

Alternative Name: HPE5

Immunogen: Recombinant protein of human ZIC2

Conjugate: Unconjugated

Modification: Unmodified