Product Description

ZMYND8 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61552-50, BS61552-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Members of the protein kinase C (PKC) family play a key regμlatory role in a variety of cellμlar functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellμlar receptors for activated PKC that serve as anchors and may be involved in the activation-induced translocation of PKC. RACK7 (receptor for activated C kinase 7), also known as ZMYND8 (zinc finger MYND domain-containing protein 8), PRKCBP1 (protein kinase C (PKC)-binding protein 1) or PRO2893, is a widely expressed protein with predominant expression in pancreas, lung, placenta and brain. RACK7 contains one bromodomain, one PHD-type zinc finger, one MYND-type zinc finger and one PWWP domain. Via its C-terminus, RACK7 interacts with PKC ∫ and is believed to play a role in PKC signaling and function as a transcription regμlator. In response to DNA damage, RACK7 is phosphorylated by ATM or ATR. In addition, mμltiple isoforms exist for RACK7.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Protein kinase C-binding protein 1, Cutaneous T-cell lymphoma-associated antigen se14-3, Rack7, Zinc finger MYND domain-containing protein 8

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 586-630 of Human ZMYND8

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Specificity: ZMYND8 polyclonal antibody detects endogenous levels of ZMYND8 protein.

Molecular Weight: ~ 190 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9μlU4

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only