Product Description

ZNF187 Polyclonal Antibody

Catalogue Numbers: BS5945-50, BS5945-100

Sizes: 50µl, 100µl

Alternative Name: Zinc finger and SCAN domain-containing protein 26; Protein SRE-ZBP; Zinc finger protein 187; ZSCAN26

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q16670

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB ICC

All Applications: WB: 1:500~1:1000
ICC: 1:50~1:200

Background: The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE). The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ZNF187 polyclonal antibody detects endogenous levels of ZNF187 protein.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ZNF187 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: Hela cell lysate
Lane 3: sp2/0 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187.

Conjugate: Unconjugated

Modification: Unmodified