Product Description

ZNF281 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-90442-60, E-AB-90442-120, E-AB-90442-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ZNF281

Target Synonym: ZNF281; ZBP-99; ZNP-99

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y2X9

Background: Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human ZNF281

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:3000

Calculated MW: 93kDa/96kDa

Observed MW: 110kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only